Author(s): Stephen P. Denyer, Norman Hodges, Sean P. Gorman, Brendan F. Gilmore
Edition: 8th
Publisher: Wiley-Blackwell
Year: 2011
Language: English
Pages: 525
Pharmaceutical
Microbiology......Page 5
Table of
Contents......Page 7
List of contributors......Page 9
Preface to the eighth edition......Page 11
Preface to the first edition......Page 12
Part 1: Biology of microorganisms......Page 13
Introduction to pharmaceutical microbiology......Page 15
Fundamental features of microbiology......Page 21
Bacteria......Page 36
Fungi......Page 56
Viruses......Page 71
Protozoa......Page 96
Part 2: Pathogens and host responses......Page 119
Principles of microbial pathogenicity and epidemiology......Page 121
Microbial biofilms: consequences for health......Page 133
Immunology......Page 143
Vaccination and immunization......Page 163
Part 3: Prescribing therapeutics......Page 179
Antibiotics and synthetic antimicrobial agents: their properties and uses......Page 181
Mechanisms of action of antibiotics and synthetic anti-infective agents......Page 212
Bacterial resistance to antibiotics......Page 229
Clinical uses of antimicrobial drugs......Page 242
Antibiotic prescribing and antibiotic stewardship......Page 260
Public health microbiology: infection prevention and control......Page 269
part 4: Contamination and infection control......Page 283
Microbial spoilage, infection risk and contamination control......Page 285
Laboratory evaluation of antimicrobial agents......Page 305
Chemical disinfectants, antiseptics and preservatives......Page 324
Non-antibiotic antimicrobial agents: mode of action and resistance......Page 346
Sterilization procedures and sterility assurance......Page 364
Part 5: Pharmaceutical production......Page 391
Sterile pharmaceutical products......Page 393
Principles of good manufacturing practice......Page 414
The manufacture and quality control of immunological products......Page 428
Recombinant DNA technology......Page 447
Part 6: Current trends and new directions......Page 473
The wider contribution of microbiology to the pharmaceutical sciences......Page 475
Alternative strategies for antimicrobial therapy......Page 495
Index......Page 507