Fundamental Immunology
Seventh Edition
This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed.
Look inside and discover…
• Fully revised and updated content reflects the latest advances in the field.
• Current insights enhance readers’ understanding of immune system function
• Unique approach bridges the gap between basic immunology and the disease process.
• Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment.
• Abundant illustrations and tables deliver essential information at a glance.
PLUS…
A convenient companion website features the fully searchable text with all references linked to PubMed.
Pick up your copy today!
Author(s): William E. Paul (editor)
Edition: 7
Publisher: LWW
Year: 2012
Language: English
Pages: 1312
Fundamental Immunology
CONTRIBUTING AUTHORS
PREFACE
ACKNOWLEDGMENTS
CONTENTS
SECTION I Introduction to Immunology
The Immune System
History of Immunology
SECTION II Organization and Evolution of the
Lymphoid Tissues and Organs
Evolution of the Immune System
SECTION III Immunoglobulins and B Lymphocytes
Immunoglobulins: Structure and Function
Immunoglobulins: Molecular Genetics
Antigen–Antibody Interactions and Monoclonal Antibodies
B-Lymphocyte Development and Biology
B-Lymphocyte Receptors, Signaling Mechanisms, and Activation
B-Lymphocyte Responses
SECTION IV T-Lymphocytes
T-Cell Antigen Receptors
Mechanisms of T-Lymphocyte Signaling and Activation
T-Lymphocyte Developmental Biology
Peripheral T Lymphocyte Responses and Function
SECTION V The Intersection of Innate and Adaptive Immunity
The Innate Immune System
Dendritic Cells
Natural Killer Cells
CD1d–Restricted Natural Killer T Cells
Macrophages and Phagocytosis
Granulocytes and Mast Cells
The Major Histocompatibility Complex and Its Proteins
Antigen Processing and Presentation
SECTION VI Induction, Regulation, and Effector Functions of the Immune Response
Immunogenicity and Antigen Structure
Fc Receptors and Their Role in Immune Regulation and Infl ammation
Type I Cytokines and Interferons, and Their Receptors
The Interleukin-1 Family
Tumor Necrosis Factor–Related Cytokines in Immunity
Chemokines
Helper T-Cell Differentiation and Plasticity
Programmed Cell Death
Immunologic Memory
Immunologic Tolerance
Regulatory/Suppressor T Cells
The Mucosal Immune System
Neurophysiologic Refl ex Mechanisms in Immunology
Complement
Cell-Mediated Cytotoxicity
SECTION VII Immunity to Infectious Agents
The Immune Response to Parasites
Immunity to Viruses
Immunity to Intracellular Bacteria
Immunity to Extracellular Bacteria
Immunology of Human Immunodefi ciency Virus Infection
Vaccines
SECTION VIII Immunologic Mechanisms in Disease
Autoimmunity and Autoimmune Diseases
Immunologic Mechanisms of Allergic Disorders
Transplantation Immunology
Cancer Immunology
Inborn Errors of Immunity
INDEX
REFERENCES
CHAPTER 2 REFERENCES
CHAPTER 3 REFERENCES
CHAPTER 4 REFERENCES
CHAPTER 5 REFERENCES
CHAPTER 6 REFERENCES
CHAPTER 7 REFERENCES
CHAPTER 8 REFERENCES
CHAPTER 9 REFERENCES
CHAPTER 10 REFERENCES
CHAPTER 11 REFERENCES
CHAPTER 12 REFERENCES
CHAPTER 13 REFERENCES
CHAPTER 14 REFERENCES
CHAPTER 15 REFERENCES
CHAPTER 16 REFERENCES
CHAPTER 17 REFERENCES
CHAPTER 18 REFERENCES
CHAPTER 19 REFERENCES
CHAPTER 20 REFERENCES
CHAPTER 21 REFERENCES
CHAPTER 22 REFERENCES
CHAPTER 23 REFERENCES
CHAPTER 24 REFERENCES
CHAPTER 25 REFERENCES
CHAPTER 26 REFERENCES
CHAPTER 27 REFERENCES
CHAPTER 28 REFERENCES
CHAPTER 29 REFERENCES
CHAPTER 30 REFERENCES
CHAPTER 31 REFERENCES
CHAPTER 32 REFERENCES
CHAPTER 33 REFERENCES
CHAPTER 34 REFERENCES
CHAPTER 35 REFERENCES
CHAPTER 36 REFERENCES
CHAPTER 37 REFERENCES
CHAPTER 38 REFERENCES
CHAPTER 39 REFERENCES
CHAPTER 40 REFERENCES
CHAPTER 41 REFERENCES
CHAPTER 42 REFERENCES
CHAPTER 43 REFERENCES
CHAPTER 44 REFERENCES
CHAPTER 45 REFERENCES
CHAPTER 46 REFERENCES
CHAPTER 47 REFERENCES
CHAPTER 48 REFERENCES
