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Essentials of bioinformatics. Volume II, In silico life science : medicine

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Author(s): Banaganapalli, Babajan; Elango, Ramu; Hakeem, Khalid Rehman; Shaik, Noor Ahmad
Publisher: Springer
Year: 2019

Language: English
Pages: 0
Tags: Bioinformatics

1. Bioinformatics strategies for molecular diagnostics o Candidate gene selection and analysis of Rare diseaseso Candidate gene selection and analysis of Complex diseases2. Bioinformatics tools for Molecular Diagnosticso Single Gene Disorders --
Case studieso Polygenic Disorders --
Case studieso Genetic Tests --
Tools, Results, Interpretation3. Bioinformatics approaches for Genetic Risk Marker Studieso Population Geneticso Gene Polymorphismso Gene Expression Assayso Genetic Statistics4. Bioinformatics for Disease Prognosticso Pharmacogeneticso Efficacyo Toxicityo Adverse reactions o Biomarker Selection and Monitoringo Precision Medicine5. Bioinformatics tools in Gene Therapyo Enzyme Replacement- Bioinformatics role is limitedo Gene Replacement (Knock-in)o Gene Silencing(RNAi)o Gene Editing (CRISPR)6. Bioinformatics tools in Disease Therapeutics --
Data analysis tools and application o Drug Discovery o Protein-Drug Interactionso Drug-Body metabolism studieso Microbiome.