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Drug Therapy for Type 2 Diabetes

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Author(s): Andrew Krentz
Year: 2012

Language: English

CONTENTS
Preface
1 Type 2 diabetes: rationale forpharmacological treatment
1. Introduction
2. Type 2 diabetes: a progressive disorder
3. Pathophysiology
4. Safety of intensive glucose-lowering strategies inhigh-risk patients
5. Therapeutic approaches
6. Guidelines and treatment algorithms
2 Established classes of glucose-loweringdrugs
1. Introduction
2. Biguanides
3. Sulphonylureas
4. Meglitinides
5. Thiazolidinediones
6. Alpha-glucosidase inhibitors
7. Fixed dose combinations of orally active drugs
8. Principles of insulin therapy in type 2 diabetes
9. Weight-reducing drugs
3 Recently introduced and emerging classesof glucose-lowering drugs
1. Drugs acting on the incretin system
2. Pathophysiology of the incretin system in type 2 diabetes
3. Dipeptidyl peptidase 4 inhibitors
4. Glucagon-like peptide 1 agonists
5. Amylin analogues
6. Bromocriptine
7. Drugs in development
4 The place of newer drugs in treatmentalgorithms
1. Recommended management of type 2 diabetes
2. Current NICE guidance: oral glucose-lowering drugs
3. NICE guidance: injectable agents
4. National and international guidelines compared
Index