The book presents a machine-generated literature review on CRISPR (clustered regularly interspaced short palindromic repeats) from 114 selected papers published by Springer Nature in the last few years, which are then organized by the book editors with a human-written introduction to each chapter. Each chapter presents summaries of predefined themes and provides the reader with a basis for further exploration of the topic. As one of the experimental projects initiated by Springer Nature for AI book content generation, this book shows the latest developments in the CRISPR field. It will be a useful reference for graduate students who are interested in CRISPR-related research and early-career researchers who need an overview of the current development of the field.
Author(s): Ziheng Zhang, Ping Wang, Ji-Long Liu
Publisher: Springer
Year: 2022
Language: English
Pages: 244
City: Singapore
Preface
Contents
1 Development and Vision of CRISPR-Based Technology
References
2 Gene Editing Through CRISPR-Based Technology
2.1 CRISPR and The Bacterial Immunity
2.2 Gene Editing and Beyond Editing
2.3 Potential Risks
References
3 Extension and Improvement of CRISPR-Based Technology
3.1 Engineering and Application of Cas Nuclease
3.2 Base Editing and Prime Editing System
3.3 Optimization of Guide RNA Design
References
4 Application of CRISPR-Based Technology in Medical Research and Disease Treatment
4.1 CRISPR in Biomedical Research
4.2 CRISPR Provides a Potential Disease Diagnosis and Treatment Strategy
References
5 Application of CRISPR-Based Technology in Plant Gene Editing and Agricultural Engineering
5.1 CRISPR-Based Gene Editing in Plants
5.2 Application of CRISPR-Based Technology in Crop Breeding
References
6 CRISPR Guides
References
