COVID-19: The Essentials of Prevention and Treatment elaborates on the ethology, pathogenesis, epidemiology, clinical characteristics, treatment principles, rehabilitation and prevention, and prevention and control measures for COVID-19. Aimed at healthcare workers, and written to be a practical guide, six chapters cover the following aspects of COVID-19: respiratory viruses; pathogenesis; case definitions and diagnosis; treatment; prevention and disease control; and prospects for the management and research of respiratory virus infections. This book gives first-hand information on the prevention, control, diagnosis and treatment of COVID-19.
COVID-19 was recognized as a pandemic in March 2020 by the World Health Organization. It is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians working in China, particularly where the outbreak was first identified in Wuhan, have built up knowledge of prevention and control measures, and diagnosis and treatment of this disease. These insights are now globally relevant. The authors of this book are senior physicians specializing in respiratory diseases, pulmonary diseases and critical care medicine, and are all clinical and scientific research experts working in China, with particular experience in Wuhan.
Author(s): Jie-Ming Qu, Bin Cao, Rong-Chang Chen
Publisher: Elsevier
Year: 2020
Language: English
Pages: 114
City: Amsterdam
Front Matter
Copyright
Author information
Prologue
Respiratory virus and COVID-19
Overview of respiratory viruses
Etiology of COVID-19
Transmission of COVID-19
Pathogenesis of COVID-19
Contents
Are there any special concerns on COVID-19 and its pathogenesis?
SARS-CoV-2 infection and cardiac injury
Other injuries
What is the role of cytokine release storm triggered by pathogens in severe and critical cases of COVID-19?
Invading organs and virus-induced infections
Clinical features of COVID-19
Contents
Clinical manifestation
Abnormal findings of laboratory tests
Abnormalities and features in imaging
Diagnosis of COVID-19
Diagnosis
Definition of suspected case
Definition of confirmed case
Clinical diagnosis
Etiological test
Respiratory tract virus detection
Nucleic acid detection for SARS-CoV-2
Problems and troubleshooting in PCR testing
Antibody detection assay for SARS-CoV-2
Severity evaluation
Differential diagnosis
Cases reporting procedure
Exclusion of cases
Treatment of COVID-19
Site of care
General care
Antivirals
Glucocorticoids
Respiratory support
General principles
HFNC
Noninvasive mechanical ventilation
Invasive mechanical ventilation
The lung protective ventilation strategy should be strictly enforced
FiO2 is initially set at 100%
ECMO
Respiratory support and respiratory therapists in the treatment of severely and critically ill patients
Convalescent plasma therapy
Cytokine-targeted therapy
Venous thromboembolism prophylaxis and treatment
Antibacterial treatment
Standards for discontinuation of isolation and hospital discharge
Prevention and disease control of COVID-19
Principles
Use of personal protective equipment
Selection of PPE
Use of masks
Use of gloves
Use of goggles and protective face shields/face screens
Use of gowns and protective clothing
The procedure for wearing protective articles when entering and leaving the isolation ward is as follows
Nosocomial infection control
Collecting and processing laboratory samples of patients with suspected COVID-19
Fangcang shelter hospitals/temporary treatment centers
Disease control on a community level
Use information and communication technology to get ahead of prevention and control
Improve the effectiveness of diagnosis and treatment with information technology
Construction of prevention and control platform
Vaccine development
Better understanding and control of new coronavirus infection
How to better understand the 2019 coronavirus disease
Improving clinical management of respiratory tract virus infection and future research agenda
Detection of respiratory tract viruses: Etiological diagnosis of lung infection and emerging infectious diseases
Establish a respiratory tract virus research platform for clinical diagnosis and treatment
Attach importance to rational selection and application of antiviral drugs
Establish a comprehensive treatment platform for severe cases life support
Develop clinical and basic research in respiratory tract virology
The need to conduct clinical research in an orderly way
The importance of PCCM discipline development to cope with the epidemic situation
Index
A
B
C
D
E
F
G
H
I
L
M
N
O
P
Q
R
S
T
V
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