This book presents contributions from the MICCAI 2021 Computational Biomechanics for Medicine Workshop. "Computational Biomechanics for Medicine - towards translation and better patient outcomes” comprises papers accepted for the MICCAI Computational Biomechanics for Medicine Workshop held virtually in conjunction with Medical Image Computing and Computer Assisted Intervention conference 2021, based in Strasbourg. The content focuses on methods and applications of computational biomechanics to medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, analysis of injury mechanisms, implant and prostheses design, as well as artificial organ design and medical robotics. This book details state-of-the-art progress in the above fields to researchers, students, and professionals.
Author(s): Poul M.F. Nielsen, Martyn P. Nash, Xinshan Li, Karol Miller, Adam Wittek
Publisher: Springer
Year: 2022
Language: English
Pages: 193
City: Cham
Preface
Contents
Solid Mechanics
Towards Accurate Measurement of Abdominal Aortic Aneurysm Wall Thickness from CT and MRI
1 Introduction
2 Methods
2.1 Patient Data
2.2 Registration of Patient CT and MRI Scans
2.3 Detection of Aortic Wall from CT and MRI
2.4 Overlaying Wall Edges of CT and MRI
2.5 Measurement of Aortic Wall Thickness
3 Results
3.1 Summary of Results
3.2 Statistical Analysis
4 Discussion and Conclusions
References
Patient-Specific Finite Element Modeling of Aneurysmal Dilatation After Chronic Type B Aortic Dissection
1 Introduction
2 Material and Methods
2.1 Constitutive and Balance Equations
2.2 Dissection Model
2.3 Finite Element Implementation
3 Numerical Applications
3.1 Validation Test Case
3.2 Application to a Cylindrical Artery
3.3 Application to a Patient-Specific Artery
3.4 Computational Details
4 Results
4.1 Validation Test Case
4.2 Application to a Cylindrical Artery
4.3 Application to a Patient-Specific Artery
5 Discussion
6 Conclusions
References
Characterizing the Biomechanics of an Endovascular Intervention in Cerebral Aneurysms Using Kirchhoff–Love Shells of Nonuniform Thickness
1 Introduction
2 Materials and Methods
2.1 AneuriskWeb Database
2.2 Geometrically Nonlinear Thin Shells Elastic Model
2.3 Localized Force
2.4 Numerical Implementation
3 Surfaces Mesh Treatment
4 Experiments and Results
5 Conclusions and Future Directions
References
Imaging-Based Patient-Specific Biomechanical Evaluation of Atherosclerosis and Aneurysm: A Comparison Between Structural-Only, Fluid-Only and Fluid–Structure Interaction Analysis
1 Introduction
2 Materials and Methods
2.1 Medical Imaging, Segmentation and 3D Reconstruction of Blood Vessels
2.2 Computational Analysis
2.3 Data Analysis
3 Results
3.1 Coronary Artery
3.2 Carotid Artery
3.3 Cerebral Artery
4 Discussion
4.1 Limitations
5 Conclusions
References
Automatic Framework for Patient-Specific Biomechanical Computations of Organ Deformation: An Epilepsy (EEG) Case Study
1 Introduction
2 Proposed Framework
2.1 Image Pre-processing
2.2 Model Construction
2.3 Model Solution
3 Case Study: Intracranial Electrodes Induced Brain Shift
4 Discussion and Conclusion
References
Generating Scoliotic Computed Tomography Volumes from Finite Element Spine Models
1 Introduction
1.1 Related Works
2 Methods
2.1 Overview
2.2 Finite Element Anatomical Meshes
2.3 Displacement and Boundary Conditions Applied to FE Meshes
2.4 Conversion of FE Meshes to Synthetic CT Volumes
3 Results
4 Conclusion
References
Morphological Variation in an Endothelial Cell Population: A Virtual-Cell Model
1 Introduction
2 Materials and Methods
2.1 Cell Culture and Imaging
2.2 Morphological Descriptors
3 Results
3.1 Spatial Descriptors
4 Discussion
References
Fluid Mechanics
Efficient and Accurate Computation of Quantitative Flow Ratio (QFR) for Physiological Assessment of Coronary Artery Stenosis from a Single Angiographic View
1 Introduction
2 Methods
2.1 Coronary Angiography
2.2 FFR Measurements
2.3 QFR Calculations
3 Numerical Results
4 Discussion
5 Conclusion
References
Predicting Plaque Progression in Patient-Specific Carotid Bifurcation
1 Introduction
2 Materials and Methods
2.1 Reconstruction of the Carotid Bifurcation
2.2 Plaque Progression Modeling
3 Results
4 Discussion and Conclusion
References
Imaging
Assessing Fibre Reorientation in Soft Tissues with Simultaneous Mueller Matrix Imaging and Mechanical Testing
1 Introduction
2 Method
3 Results and Discussion
4 Conclusion
References
A Direct Geometry Processing Cartilage Generation Method Using Segmented Bone Models from Datasets with Poor Cartilage Visibility
1 Introduction
2 Related Work
3 Methodology
3.1 Distance Filtering
3.2 Curvature-Based Region Filling
3.3 Extrusion
3.4 Harmonic Boundary Blending
4 Results
5 Discussion and Conclusion
References
Development of an Open Source, Low-Cost Imaging System for Continuous Lung Monitoring
1 Introduction
2 Methodologies
2.1 EIT Measurement
2.2 Reference Volume Measurement
2.3 Lidar Scanning and Mesh Generation
2.4 Test Procedure
3 Reconstruction and Results
4 Discussion
5 Conclusions
References
Measuring Three-Dimensional Surface Deformations of Skin Using a Stereoscopic System and Intrinsic Features
1 Introduction
2 Method
2.1 Stereoscopic Imaging Device
2.2 Multi-Camera Calibration
2.3 Measuring Deformations Using 3D DIC
2.4 Validation Tests for Geometry and Translational Shifts
2.5 Practical Experimentation of the System on Membranes
3 Results
3.1 Validation Tests for Reconstructed Geometry and Translation
3.2 Soft Material Experiments
4 Discussion
References
Index
