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Biomolecular Crystallography

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Author(s): Bernhard Rupp
Edition: First
Publisher: Garland Science
Year: 2018

Language: English
Pages: 832

PART I: FROM SEQUENCE TO CRYSTALS
1. Introduction: Preparing Your Study
2. Protein Structure
3. Protein Crystallization
4. Proteins for Crystallography

PART II: FUNDAMENTALS OF PROTEIN CRYSTALLOGRAPHY
5. Crystal Geometry
6. Diffraction Basics
7. Statistics and Probability in Crystallography

PART III: FROM CRYSTALS TO DATA
8. Instrumentation and Data Collection

PART IV: DETERMINING YOUR STRUCTURE
9. Reconstruction of Electron Density and the Phase Problem
10. Experimental Phasing
11. Non-Crystallographic Symmetry and Molecular Replacement
12. Model Building and Refinement

PART V: MAKING SENSE OF YOUR STRUCTURE
13. Structure Validation, Analysis, and Presentation