Comprehensive resource on the latest and most important developments in the highly vivid field of asymmetric organocatalysis
The book provides a comprehensive overview of the most important advancements in the field of asymmetric organocatalysis that have occurred within the last decade. It presents valuable examples of newly developed synthetic methodologies based on various organocatalytic activation modes.
Special emphasis is given to strategies where organocatalysis is expanding its potential by pushing the boundaries and founding new synergistic interactions with other fields of synthetic chemistry, such as metal catalysis, photocatalysis, and biocatalysis. The application of different concepts (such as vinylogy, dearomatization, or cascade reactivity), resulting in the development of new functionalization strategies, is also discussed. Sample topics covered within the book include:
- New developments in enantioselective Brønsted acid catalysis with strong hydrogen-bond donors
- Asymmetric phase-transfer catalysis, from classical applications to new concepts
- Halogen-bonding organocatalysis
- Asymmetric electrochemical organocatalysis and synergistic organo-organocatalysis
- Immobilized organocatalysts for enantioselective continuous flow processes
- Mechanochemistry and high-pressure techniques in asymmetric organocatalysis
- Useful tools in elucidation of organocatalytic reaction mechanisms
With an overall focus on new reactions and catalysts, this two-volume work is an indispensable source for everyone working in the field of asymmetric organocatalysis.