Here is an informative overview of diabetes mellitus in conjunction with plant-based treatments. It discusses available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches.
The book begins with an introduction to diabetes, giving a brief overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with ethnobotanical information. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects of active plantbased antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques.
Author(s): Deepu Pandita, Anu Pandita, Chander Bhanu
Publisher: CRC Press/Apple Academic Press
Year: 2022
Language: English
Pages: 476
City: Palm Bay
Cover
Half Title
Title
Copyright
About the Editors
Contents
Contributors
Abbreviations
Preface
Part I: Introduction of Metabolic Disorder Diabetes
1. Diabetes Mellitus: History, Diagnosis, Classification, Pathophysiology, and Risk Factors
2. Diabetes Mellitus: Signs and Symptoms, Epidemiology, Current Prevention, Management Therapies, and Treatments
Part II: Antidiabetic Plants in Systems of Traditional Knowledge
3. The ‘Green Healers’ of Diabetes Mellitus: An Ayurvedic Eye
4. Concept of Diabetes Mellitus and Antidiabetic Plant in the Unani System of Medicine
5. Omics Technology in Antidiabetic Plant Research
6. Ethnobotanical Information of Medicinal Plants Used for Diabetes Mellitus in Seshachalam Biosphere Reserve, Andhra Pradesh, India
Part III: Mode of Action
7. Overview of Steviol Glycosides: Action Toward Diabetes Control
8. Mechanism of Action of the Traditional and Modern Phyto-Biotics in the Treatment of Diabetes in the Current Era
9. Molecular Insights of Active Plant-Based Antidiabetic Drug Molecules
Part IV: Recent Biotechnological Advancements of Antidiabetic Plants and Plant-Based Anti-Diabetes Drugs and Future Perspectives with Genome Editing Technologies
10. Molecular Breeding and Application of Molecular Markers for Improvement of Antidiabetic Medicinal Plants
11. Biotechnologically Engineered Transgenic Medicinal Plants: Exploration of Antidiabetic Properties
12. Transcriptomic Studies of Medicinal Plants Elucidating Their Role in Diabetes
13. How Metabolomics Shapes the Future of Drugs in Antidiabetic Plants
14. Zinc Finger Nuclease Based Genome Editing in Enhancement of Antidiabetic Activity of Plants: Prospective Applications
15. Transcription Activator-Like Effector Nucleases (TALENs): Genome Editing Tool to Explore Enhanced Activity of Antidiabetic Plants
Index
