Antibiotics Simplified

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Author(s): Jason C. Gallagher, Conan MacDougall
Edition: 4 ed.
Publisher: Jones & Bartlett Learning
Year: 2016

Language: English
Pages: 289

Title Page......Page 2
Copyright Page......Page 3
Contents......Page 6
Acknowledgments......Page 10
Introduction......Page 11
New to the Fourth Edition......Page 14
PART 1: Considerations with Antibiotic Therapy......Page 15
Chapter 1: The Wonderful World of Microbiology......Page 16
Chapter 2: General Approach to Infectious Diseases......Page 23
Chapter 3: Antibiotic Pharmacokinetics......Page 31
Chapter 4: Antibiotic Pharmacodynamics......Page 39
Chapter 5: Adverse Consequences of Antibiotic Use......Page 46
Chapter 6: Antibiotic Resistance......Page 49
PART 2: Antibacterial Drugs......Page 57
Chapter 7: Beta-Lactams......Page 58
Penicillins......Page 59
Natural Penicillins......Page 60
Antistaphylococcal Penicillins......Page 62
Aminopenicillins......Page 64
Antipseudomonal Penicillins......Page 66
Penicillin/Beta-Lactamase Inhibitor Combinations......Page 68
Cephalosporins......Page 71
First-Generation Cephalosporins......Page 72
Second-Generation Cephalosporins......Page 73
Third-Generation Cephalosporins......Page 75
Fourth-Generation Cephalosporins......Page 78
Anti-MRSA Cephalosporins......Page 79
Cephalosporin/Beta-Lactamase Inhibitor Combinations......Page 81
Carbapenems......Page 83
Monobactams......Page 86
Chapter 8: Glycopeptides and Short-Acting Lipoglycopeptides......Page 88
Chapter 9: Long-Acting Glycopeptides......Page 92
Chapter 10: Fluoroquinolones......Page 94
Chapter 11: Aminoglycosides......Page 98
Chapter 12: Tetracyclines and Glycylcyclines......Page 102
Chapter 13: Macrolides and Ketolides......Page 106
Chapter 14: Oxazolidinones......Page 109
Chapter 15: Nitroimidazoles......Page 111
Chapter 16: Nitrofurans and Fosfomycin......Page 114
Chapter 17: Streptogramins......Page 117
Chapter 18: Cyclic Lipopeptides......Page 120
Chapter 19: Folate Antagonists......Page 123
Chapter 20: Lincosamides......Page 127
Chapter 21: Polymyxins......Page 130
Chapter 22: Fidaxomicin......Page 133
PART 3: Antimycobacterial Drugs......Page 135
Chapter 23: Antimycobacterial Drugs......Page 136
Chapter 24: Rifamycins......Page 139
Chapter 25: Isoniazid......Page 143
Chapter 26: Pyrazinamide......Page 145
Chapter 27: Ethambutol......Page 147
PART 4: Antifungal Drugs......Page 149
Chapter 28: Antifungal Drugs......Page 150
Chapter 29: Polyenes......Page 153
Chapter 30: Antifungal Antimetabolites......Page 156
Fluconazole......Page 159
Itraconazole......Page 161
Voriconazole......Page 163
Posaconazole......Page 165
Isavuconazole......Page 167
Chapter 32: Echinocandins......Page 172
PART 5: Antiviral Drugs......Page 175
Chapter 33: Antiviral Drugs......Page 176
Chapter 34: Anti-Herpes Simplex Virus and Varicella-Zoster Virus Agents......Page 179
Chapter 35: Anti-cytomegalovirus Agents......Page 181
Chapter 36: Neuraminidase Inhibitors......Page 185
Nucleoside and Nucleotide Reverse Transcriptase Inhibitors......Page 187
Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)......Page 190
Protease Inhibitors......Page 193
Integrase Inhibitors......Page 197
Entry and Fusion Inhibitors......Page 199
Chapter 38: Antiviral Interferons......Page 201
Chapter 39: Direct-Acting Anti-hepatitis C Agents......Page 204
Chapter 40: Ribavirin......Page 209
Chapter 41: Hepatitis B Nucleoside Analogs......Page 211
PART 6: Antiparasitic Drugs......Page 213
Chapter 42: Antiparasitic Drugs......Page 214
Chapter 43: Quinolines......Page 217
Chapter 44: Atovaquone......Page 221
Chapter 45: Benzimidazoles......Page 223
Chapter 46: Pentamidine......Page 225
Chapter 47: Ivermectin......Page 228
Appendix 1: Selected Normal Human Flora......Page 230
Appendix 2: Spectrum of Activity......Page 231
Appendix 3: Empiric Regimens for Common Infections......Page 236
Index......Page 241