Alternative Medicines for Diabetes Management: Advances in Pharmacognosy and Medicinal Chemistry

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Apart from diet and exercise, the strategic use of different classes of prescribed or non-prescribed xenobiotic compounds for the restoration of euglycemic levels in the body is well known. The ongoing rivalry between the recommended usage of allopathic medicines versus ayurvedic remedies has encouraged many researchers to focus their studies on thoroughly isolating and characterizing the extracts from different parts of plants and then evaluating their relative activities via in vitro, in vivo and in some cases clinical studies. Alternative Medicines for Diabetes Management: Advances in Pharmacognosy and Medicinal Chemistry provides a holistic view of all oral therapies for diabetes mellitus that are available to the public by removing the silos and stigmas that are associated with both allopathic and ayurvedic medicines. Additional Features Include Highlights the potential role of dietary and medicinal plant materials in the prevention, treatment, and control of diabetes and its complications. Educates readers on the benefits and shortcomings of the various present and potential oral therapies for diabetes mellitus. Allows quick identification and retrieval of material by researchers learning the efficacy, associated dosage and toxicity of each of the classes of compounds. Presents the history, nomenclature, mechanisms of action and shortcomings for each of the various sub-classes of allopathic therapeutants for diabetes mellitus and then introduces ayurvedic medicines. Section C discusses various metallopharmaceuticals and provides a holistic view of all available and potential therapies for the disease.

Author(s): Varma H. Rambaran, Nalini K. Singh
Series: Medicinal Plants and Natural Products for Human Health
Publisher: CRC Press
Year: 2022

Language: English
Pages: 234
City: Boca Raton

Cover
Half Title
Series Page
Title Page
Copyright Page
Dedication
Table of Contents
Preface
Acknowledgements
Authors
Chapter 1 Etiology
1.1 Diabetes Mellitus (DM)
1.1.1 Type-1 Diabetes
1.1.2 Type-2 Diabetes
1.1.3 Hyperglycaemia in Pregnancy
1.1.4 Other Types of Diabetes
1.2 Insulin Transduction Pathway
1.3 Our Goal
Chapter 2 Allopathic Medicines
2.1 Introduction
2.1.1 Overview and Significance
2.1.2 History
2.1.3 Downfalls
2.2 Biguanides
2.3 Sulfonylureas
2.4 Meglitinides
2.5 Alpha-Glucosidase Inhibitors
2.6 DPP-4 Inhibitors
2.7 Thiazolidinedione
2.8 SGLT-2 Inhibitors
Chapter 3 Ayurvedic Medicines: (Ethnopharmacological Treatments)
3.1 Introduction
3.1.1 Overview and Significance
3.1.2 History
3.1.2.1 Traditional Indian Medicine
3.1.2.2 Traditional Chinese Medicine
3.1.2.3 Traditional Arabic and Islamic Medicine
3.1.3 Downfalls
3.2 Abelmoschus esculentus Linn. (AE)
3.3 Ageratum conyzoides Linn. (AgC)
3.4 Allium cepa Linn. (AC)
3.5 Allium sativum Linn. (AS)
3.6 Aloe barbadensis Mill. (ABM)
3.7 Annona muricata Linn. (AM)
3.8 Apium graveolens Linn. (AG)
3.9 Azadirachta indica Linn. (AI)
3.10 Bidens pilosa Linn. (BiP)
3.11 Bixa orellana Linn. (BO)
3.12 Brassica juncea Linn. (BJ)
3.13 Bryophyllum pinnatum Linn. (BP)
3.14 Capparis spinosa Linn. (CaS)
3.15 Carica papaya Linn. (CaP)
3.16 Catharanthus roseus Linn. (CR)
3.17 Cecropia obtusifolia Linn. (CeO) and Cecropia peltata Linn. (CeP)
3.18 Centella asiatica Linn. (CeA)
3.19 Chromolaena odorata Linn. (CO)
3.20 Citrus aurantiifolia Linn. (CiA)
3.21 Citrus limon Linn. (Cil)
3.22 Citrus paradisi Linn. (CiP)
3.23 Citrus sinensis Linn. (CiS)
3.24 Coriandrum sativum Linn. (CoS)
3.25 Crescentia cujete Linn. (CrC)
3.26 Cucumis sativus Linn. (CS)
3.27 Cucurbita ficifolia Linn. (CF) and Cucurbita pepo Linn. (CP)
3.28 Curcuma longa Linn. (CL)
3.29 Cymbopogon citratus Linn. (CC)
3.30 Euphorbia hirta Linn. (EH)
3.31 Hibiscus rosa-sinensis Linn. (HRS)
3.32 Justicia secunda Vahl (JS)
3.33 Lantana camara Linn. (LC)
3.34 Leonotis nepetifolia Linn. (LN)
3.35 Mangifera indica Linn. (MI)
3.36 Mentha
3.37 Mimosa pudica Linn. (MP)
3.38 Momordica charantia Linn. (MC)
3.39 Morinda Citrifolia Linn. (MoC)
3.40 Moringa oleifera Linn. (MO)
3.41 Murraya koenigii Linn. (MK)
3.42 Neurolaena lobata Linn. (NL)
3.43 Ocimum gratissimum Linn. (OG) and Ocimum tenuiflorum Linn. (OT)
3.44 Panax ginseng Linn. (PG) and Panax quinquefolius Linn. (PQ)
3.45 Parthenium hysterophorus Linn. (PaH)
3.46 Peperomia pellucida Linn. (PP)
3.47 Phyllanthus amarus Linn. (PA)
3.48 Scoparia dulcis Linn. (SD)
3.49 Senna italica Linn. (SI)
3.50 Stachytarpheta jamaicensis Linn. (SJ)
3.51 Syzygium cumini Linn. (SC)
3.52 Tamarindus indica Linn. (TI)
3.53 Tournefortia hirsutissima Linn. (TH)
3.54 Urena lobata Linn. (UL)
3.55 Zingiber officinale Linn. (ZO)
Chapter 4 Metallopharmaceuticals
4.1 Introduction
4.1.1 Overview and Significance
4.1.2 The Challenge
4.1.3 The Future for Insulin-Enhancing Drugs?
4.2 Vanadium
4.3 Chromium
4.4 Zinc
4.5 Cobalt
4.6 Tungsten
4.7 Molybdenum
Conclusion
Bibliography
Abbreviations
Glossary
Index